Publications

2024

Song, J., Jonsson, L., Lu, Y., Bergen, S. E., Karlsson, R., Smedler, E., Gordon-Smith, K., Jones, I., Jones, L., Craddock, N., Sullivan, P. F., Lichtenstein, P., Di Florio, A., & Landén, M. (2024). Key subphenotypes of bipolar disorder are differentially associated with polygenic liabilities for bipolar disorder, schizophrenia, and major depressive disorder. Molecular psychiatry, 10.1038/s41380-024-02448-1. Advance online publication. https://doi.org/10.1038/s41380-024-02448-1

2023

Perry, A., Gordon-Smith, K., Lewis, K. J. S., Di Florio, A., Craddock, N., Jones, L., & Jones, I. (2023). Perinatal sleep disruption and postpartum psychosis in bipolar disorder: Findings from the UK BDRN Pregnancy Study. Journal of affective disorders, 346, 21–27. Advance online publication. https://doi.org/10.1016/j.jad.2023.11.005

Gordon-Smith, K., Hampshire, C., Mahoney, B., Perry, A., Lewis, K. J. S., Craddock, N., Jones, I., & Jones, L. (2023). Opportunities to engage in positive activities during the COVID-19 pandemic: Perspectives of individuals with mood disorders. Journal of affective disorders, S0165-0327(23)01324-1. Advance online publication.

Guintivano, J., Byrne, E. M., Kiewa, J., Yao, S., Bauer, A. E., Aberg, K. A., Adams, M. J., Campbell, A., Campbell, M. L., Choi, K. W., Corfield, E. C., Havdahl, A., Hucks, D., Koen, N., Lu, Y., Mægbæk, M. L., Mullaert, J., Peterson, R. E., Raffield, L. M., Sallis, H. M., … Sullivan, P. (2023). Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression. The American journal of psychiatry, appiajp20230053. Advance online publication.

Allardyce, J., Cardno, A. G., Gordon-Smith, K., Jones, L., Di Florio, A., Walters, J. T. R., Holmans, P. A., Craddock, N. J., Jones, I., Owen, M. J., Escott-Price, V., & O’Donovan, M. C. (2023). Specificity of polygenic signatures across symptom dimensions in bipolar disorder: an analysis of UK Bipolar Disorder Research Network data. The lancet. Psychiatry, 10(8), 623–631. https://doi.org/10.1016/S2215-0366(23)00186-4

Docherty, AR., Mullins, N., Ashley-Koch, A., Qin, X., Coleman, J., Andrey Shabalin, A.,… , Ruderfer, D. (2023). Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factors. The American Journal of Psychiatry. In press

Johnson, J., Hope, L., Jones, L., & Bradley, E. (2023). A mixed methods study to understand perinatal mental healthcare referral decisions among midwives and health visitors in the UK. Frontiers in psychiatry14, 1056987. https://doi.org/10.3389/fpsyt.2023.1056987

Casanova Dias, M., Kelson, M., Gordon-Smith, K., Perry, A., Craddock, N., Jones, L., Di Florio, A., & Jones, I. (2023). Borderline personality traits are differently associated with postpartum psychosis and postpartum depression episodes in women with bipolar disorder. Journal of affective disorders328, 81–86. https://doi.org/10.1016/j.jad.2023.01.124

Gordon-Smith, K., Saunders, K. E. A., Morton, T., Savage, J., South, M., Geddes, J., Craddock, N., Jones, I., & Jones, L. (2023). User perspectives on long-term remote active electronic self-monitoring of mood symptoms in bipolar spectrum disorders. Journal of affective disorders324, 325–333. https://doi.org/10.1016/j.jad.2022.12.090

Lewis, K. J. S., Tilling, K., Gordon-Smith, K., Saunders, K. E. A., Di Florio, A., Jones, L., Jones, I., O’Donovan, M. C., & Heron, J. (2023). The dynamic interplay between sleep and mood: an intensive longitudinal study of individuals with bipolar disorder. Psychological medicine53(8), 3345–3354. https://doi.org/10.1017/S0033291721005377

2022

Richards, A. L., Cardno, A., Harold, G., Craddock, N. J., Di Florio, A., Jones, L., Gordon-Smith, K., Jones, I., Sellers, R., Walters, J. T. R., Holmans, P. A., Owen, M. J., & O’Donovan, M. C. (2022). Genetic Liabilities Differentiating Bipolar Disorder, Schizophrenia, and Major Depressive Disorder, and Phenotypic Heterogeneity in Bipolar Disorder. JAMA psychiatry79(10), 1032–1039. https://doi.org/10.1001/jamapsychiatry.2022.2594

Mallard, T. T., Karlsson Linnér, R., Grotzinger, A. D., Sanchez-Roige, S., Seidlitz, J., Okbay, A., de Vlaming, R., Meddens, S. F. W., Palmer, A. A., Davis, L. K., Tucker-Drob, E. M., Kendler, K. S., Keller, M. C., Koellinger, P. D., & Harden, K. P. (2022). Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities. Cell Genomics2(6), 100140. https://doi.org/10.1016/J.XGEN.2022.100140

Bolton, S., Joyce, D. W., Gordon-Smith, K., Jones, L., Jones, I., Geddes, J., & Saunders, K. E. A. (2022). Psychosocial markers of age at onset in bipolar disorder: a machine learning approach. BJPsych Open8(4), e133. https://doi.org/10.1192/BJO.2022.536

Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., St Clair, D., Lencz, T., Mowry, B. J., Periyasamy, S., Cairns, M. J., Tooney, P. A., Wu, J. Q., Kelly, B., Kirov, G., Sullivan, P. F., Corvin, A., Riley, B. P., Esko, T., … Geschwind, D. (2022). Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders. Biological Psychiatry91(1), 102–117. https://doi.org/10.1016/j.biopsych.2021.02.972

Grotzinger, A. D., Mallard, T. T., Akingbuwa, W. A., Ip, H. F., Adams, M. J., Lewis, C. M., McIntosh, A. M., Grove, J., Dalsgaard, S., Lesch, K.-P., Strom, N., Meier, S. M., Mattheisen, M., Børglum, A. D., Mors, O., Breen, G., Mattheisen, M., Mors, O., Meier, S. M., … Nivard, M. G. (2022). Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis. Nature Genetics54(5), 548–559. https://doi.org/10.1038/s41588-022-01057-4

Lewis, K. J. S., Gordon-Smith, K., Saunders, K. E. A., Dolman, C., South, M., Geddes, J., Craddock, N., Di Florio, A., Jones, I., & Jones, L. (2022). Mental health prior to and during the COVID-19 pandemic in individuals with bipolar disorder: Insights from prospective longitudinal data. Bipolar disorders24(6), 658–666. https://doi.org/10.1111/bdi.13204

Mullins, N., Kang, J. E., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., Su, M. H., Watson, H. J., Adams, M., Awasthi, S., Gandal, M., Hafferty, J. D., Hishimoto, A., Kim, M., Okazaki, S., … Willour, V. (2022). Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biological Psychiatry91(3), 313–327. https://doi.org/10.1016/j.biopsych.2021.05.029

Palmer, D. S., Howrigan, D. P., Chapman, S. B., Adolfsson, R., Bass, N., Blackwood, D., Boks, M. P. M., Chen, C. Y., Churchhouse, C., Corvin, A. P., Craddock, N., Curtis, D., di Florio, A., Dickerson, F., Freimer, N. B., Goes, F. S., Jia, X., Jones, I., Jones, L., … Neale, B. M. (2022). Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia. Nature Genetics54(5), 541–547. https://doi.org/10.1038/s41588-022-01034-x

Zhu, Y., Wang, M. J., Crawford, K. M., Ramírez-Tapia, J. C., Lussier, A. A., Davis, K. A., de Leeuw, C., Takesian, A. E., Hensch, T. K., Smoller, J. W., & Dunn, E. C. (2022). Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depression. Neuropsychopharmacology47(2), 497–506. https://doi.org/10.1038/s41386-021-01172-6

2021


Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., … Rietschel, M. (2021). Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders. Molecular Psychiatry26(4), 1286–1298. https://doi.org/10.1038/s41380-019-0558-2

Byrne, E. M., Zhu, Z., Qi, T., Skene, N. G., Bryois, J., Pardinas, A. F., Stahl, E., Smoller, J. W., Rietschel, M., Owen, M. J., Walters, J. T. R., O’Donovan, M. C., McGrath, J. G., Hjerling-Leffler, J., Sullivan, P. F., Goddard, M. E., Visscher, P. M., Yang, J., & Wray, N. R. (2021). Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders. Molecular Psychiatry26(6), 2070–2081. https://doi.org/10.1038/s41380-020-0705-9

di Florio, A., Mei Kay Yang, J., Crawford, K., Bergink, V., Leonenko, G., Pardiñas, A. F., Escott-Price, V., Gordon-Smith, K., Owen, M. J., Craddock, N., Jones, L., O’Donovan, M., & Jones, I. (2021). Post-partum psychosis and its association with bipolar disorder in the UK: a case-control study using polygenic risk scores. The Lancet Psychiatry8(12), 1045–1052. https://doi.org/10.1016/S2215-0366(21)00253-4

Garvert, L., Baune, B. T., Berger, K., Boomsma, D. I., Breen, G., Greinacher, A., Hamilton, S. P., Levinson, D. F., Lewis, C. M., Lucae, S., Magnusson, P. K. E., Martin, N. G., McIntosh, A. M., Mors, O., Müller-Myhsok, B., Penninx, B. W. J. H., Perlis, R. H., Pistis, G., Potash, J. B., Preisig, M., … Van der Auwera, S. (2021). The association between genetically determined ABO blood types and major depressive disorder. Psychiatry research299, 113837. https://doi.org/10.1016/j.psychres.2021.113837

Giannakopoulou, O., Lin, K., Meng, X., Su, M. H., Kuo, P. H., Peterson, R. E., Awasthi, S., Moscati, A., Coleman, J. R. I., Bass, N., Millwood, I. Y., Chen, Y., Chen, Z., Chen, H. C., Lu, M. L., Huang, M. C., Chen, C. H., Stahl, E. A., Loos, R. J. F., … Kuchenbaecker, K. (2021). The Genetic Architecture of Depression in Individuals of East Asian Ancestry: A Genome-Wide Association Study. JAMA Psychiatry78(11), 1258–1269. https://doi.org/10.1001/jamapsychiatry.2021.2099

Gordon-Smith, K., Ridley, P., Perry, A., Craddock, N., Jones, I., & Jones, L. (2021). Migraine associated with early onset postpartum depression in women with major depressive disorder. Archives of Women’s Mental Health24(6), 949–955. https://doi.org/10.1007/s00737-021-01131-6

Gordon-Smith, K., Saunders, K. E., Savage, J., Craddock, N., Jones, I., & Jones, L. (2021). Have I argued with my family this week?”: What questions do those with lived experience choose to monitor their bipolar disorder? Journal of Affective Disorders281, 918–925. https://doi.org/10.1016/j.jad.2020.11.034

Jia, X., Goes, F. S., Locke, A. E., Palmer, D., Wang, W., Cohen-Woods, S., Genovese, G., Jackson, A. U., Jiang, C., Kvale, M., Mullins, N., Nguyen, H., Pirooznia, M., Rivera, M., Ruderfer, D. M., Shen, L., Thai, K., Zawistowski, M., Zhuang, Y., … Scott, L. J. (2021). Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Molecular Psychiatry26(9), 5239–5250. https://doi.org/10.1038/s41380-020-01006-9

Kalman, J. L., Loohuis, L. M. O., Vreeker, A., McQuillin, A., Stahl, E. A., Ruderfer, D., Grigoroiu-Serbanescu, M., Panagiotaropoulou, G., Ripke, S., Bigdeli, T. B., Stein, F., Meller, T., Meinert, S., Pelin, H., Streit, F., Papiol, S., Adams, M. J., Adolfsson, R., Adorjan, K., … Ophoff, R. A. (2021). Characterisation of age and polarity at onset in bipolar disorder. British Journal of Psychiatry219(6), 659–669. https://doi.org/10.1192/bjp.2021.102

Lussier, A. A., Hawrilenko, M., Wang, M. J., Choi, K. W., Cerutti, J., Zhu, Y., & Dunn, E. C. (2021). Genetic susceptibility for major depressive disorder associates with trajectories of depressive symptoms across childhood and adolescence. Journal of Child Psychology and Psychiatry and Allied Disciplines62(7), 895–904. https://doi.org/10.1111/jcpp.13342

Martin, J., Asjadi, K., Hubbard, L., Kendall, K., Pardiñas, A. F., Jermy, B., Lewis, C. M., Baune, B. T., Boomsma, D. I., Hamilton, S. P., Lucae, S., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Mehta, D., Mors, O., Mullins, N., Penninx, B. W. J. H., Preisig, M., Rietschel, M., … Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression. PloS one16(9), e0248254. https://doi.org/10.1371/journal.pone.0248254

Melhuish Beaupre, L. M., Tiwari, A. K., Gonçalves, V. F., Zai, C. C., Marshe, V. S., Lewis, C. M., Martin, N. G., McIntosh, A. M., Adams, M. J., Baune, B. T., Levinson, D. F., Boomsma, D. I., Penninx, B. W. J. H., Breen, G., Hamilton, S., Awasthi, S., Ripke, S., Jones, L., Jones, I., Byrne, E. M., … Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (2021). Potential Genetic Overlap Between Insomnia and Sleep Symptoms in Major Depressive Disorder: A Polygenic Risk Score Analysis. Frontiers in psychiatry12, 734077. https://doi.org/10.3389/fpsyt.2021.734077

Miles, A. E., dos Santos, F. C., Byrne, E. M., Renteria, M. E., McIntosh, A. M., Adams, M. J., Pistis, G., Castelao, E., Preisig, M., Baune, B. T., Schubert, K. O., Lewis, C. M., Jones, L. A., Jones, I., Uher, R., Smoller, J. W., Perlis, R. H., Levinson, D. F., Potash, J. B., … Nikolova, Y. S. (2021). Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk. Neuropsychopharmacology,46(13), 2304–2311. https://doi.org/10.1038/s41386-021-01189-x

Mullins, N., Forstner, A. J., O’Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., Charney, A. W., Drange, O. K., Gandal, M. J., Hagenaars, S. P., Ikeda, M., Kamitaki, N., Kim, M., Krebs, K., Panagiotaropoulou, G., … Andreassen, O. A. (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics53(6), 817–829. https://doi.org/10.1038/s41588-021-00857-4

Musliner, K. L., Andersen, K. K., Agerbo, E., Albiñana, C., Vilhjalmsson, B. J., Rajagopal, V. M., Bybjerg-Grauholm, J., Bækved-Hansen, M., Pedersen, C. B., Pedersen, M. G., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B., … Suppli, N. P. (2023). Polygenic liability, stressful life events and risk for secondary-treated depression in early life: a nationwide register-based case-cohort study. Psychological medicine53(1), 217–226. Epub May 2021 https://doi.org/10.1017/S0033291721001410

Ni, G., Zeng, J., Revez, J. A., Wang, Y., Zheng, Z., Ge, T., Restuadi, R., Kiewa, J., Nyholt, D. R., Coleman, J. R. I., Smoller, J. W., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., … Pedersen, N. L. (2021). A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts. Biological Psychiatry90(9), 611–620. https://doi.org/10.1016/j.biopsych.2021.04.018

Perry, A., Gordon-Smith, K., di Florio, A., Craddock, N., Jones, L., & Jones, I. (2021). Mood episodes in pregnancy and risk of postpartum recurrence in bipolar disorder: The Bipolar Disorder Research Network Pregnancy Study. Journal of Affective Disorders294, 714–722. https://doi.org/10.1016/j.jad.2021.07.067

Perry, A., Gordon-Smith, K., Jones, L., & Jones, I. (2021). Phenomenology, Epidemiology and Aetiology of Postpartum Psychosis: A Review. Brain sciences11(1), 47. https://doi.org/10.3390/brainsci11010047

Saunders, K. E. A., Jones, T., Perry, A., di Florio, A., Craddock, N., Jones, I., Gordon-Smith, K., & Jones, L. (2021). The influence of borderline personality traits on clinical outcomes in bipolar disorder. Bipolar Disorders23(4), 368–375. https://doi.org/10.1111/bdi.12978

Zai, C. C., Fabbri, C., Hosang, G. M., Zhang, R. S., Koyama, E., de Luca, V., Tiwari, A. K., King, N., Strauss, J., Jones, I., Jones, L., Breen, G., Farmer, A. E., McGuffin, P., Vincent, J. B., Kennedy, J. L., & Lewis, C. M. (2021). Genome-wide association study of suicidal behaviour severity in mood disorders. World Journal of Biological Psychiatry22(9), 722–731. https://doi.org/10.1080/15622975.2021.1907711

2020


Adams, M. J., Howard, D. M., Luciano, M., Clarke, T. K., Davies, G., Hill, W. D., Smith, D., Deary, I. J., Porteous, D. J., & McIntosh, A. M. (2020). Genetic stratification of depression by neuroticism: Revisiting a diagnostic tradition. Psychological Medicine50(15), 2526–2535. https://doi.org/10.1017/S0033291719002629

Akingbuwa, W. A., Hammerschlag, A. R., Jami, E. S., Allegrini, A. G., Karhunen, V., Sallis, H., Ask, H., Askeland, R. B., Baselmans, B., Diemer, E., Hagenbeek, F. A., Havdahl, A., Hottenga, J. J., Mbarek, H., Rivadeneira, F., Tesli, M., van Beijsterveldt, C., Breen, G., Lewis, C. M., … Middeldorp, C. M. (2020). Genetic Associations between Childhood Psychopathology and Adult Depression and Associated Traits in 42998 Individuals: A Meta-analysis. JAMA Psychiatry77(7), 715–728. https://doi.org/10.1001/jamapsychiatry.2020.0527

Cai, N., Revez, J. A., Adams, M. J., Andlauer, T. F. M., Breen, G., Byrne, E. M., Clarke, T. K., Forstner, A. J., Grabe, H. J., Hamilton, S. P., Levinson, D. F., Lewis, C. M., Lewis, G., Martin, N. G., Milaneschi, Y., Mors, O., Müller-Myhsok, B., Penninx, B. W. J. H., Perlis, R. H., … Flint, J. (2020). Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nature Genetics52(4), 437–447. https://doi.org/10.1038/s41588-020-0594-5

Choi, K. W., Chen, C. Y., Ursano, R. J., Sun, X., Jain, S., Kessler, R. C., Koenen, K. C., Wang, M. J., Wynn, G. H., Campbell-Sills, L., Stein, M. B., & Smoller, J. W. (2020). Prospective study of polygenic risk, protective factors, and incident depression following combat deployment in US Army soldiers. Psychological Medicine50(5), 737–745. https://doi.org/10.1017/S0033291719000527

Choi, K. W., Stein, M. B., Nishimi, K. M., Ge, T., Coleman, J. R. I., Chen, C. Y., Ratanatharathorn, A., Zheutlin, A. B., Dunn, E. C., Breen, G., Koenen, K. C., Smoller, J. W., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., … Wilson, C. H. (2020). An exposure-wide and mendelian randomization approach to identifying modifiable factors for the prevention of depression. American Journal of Psychiatry177(10), 944–954. https://doi.org/10.1176/appi.ajp.2020.19111158

Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., … Breen, G. (2020). The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls. Biological Psychiatry88(2), 169–184. https://doi.org/10.1016/j.biopsych.2019.10.015

Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., … Eley, T. C. (2020). Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Molecular Psychiatry25(7), 1430–1446. https://doi.org/10.1038/s41380-019-0546-6

di Florio, A., Lewis, K. J. S., Richards, A., Karlsson, R., Leonenko, G., Jones, S. E., Jones, H. J., Gordon-Smith, K., Forty, L., Escott-Price, V., Owen, M. J., Weedon, M. N., Jones, L., Craddock, N., Jones, I., Landén, M., & O’Donovan, M. C. (2020). Comparison of Genetic Liability for Sleep Traits among Individuals with Bipolar Disorder i or II and Control Participants. JAMA Psychiatry77(3), 303–310. https://doi.org/10.1001/jamapsychiatry.2019.4079

Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., … Børglum, A. D. (2020). Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression. Biological Psychiatry87(5), 419–430. https://doi.org/10.1016/j.biopsych.2019.06.031

Gordon-Smith, K., Lewis, K. J. S., Vallejo Auñón, F. M., di Florio, A., Perry, A., Craddock, N., Jones, I., & Jones, L. (2020). Patterns and clinical correlates of lifetime alcohol consumption in women and men with bipolar disorder: Findings from the UK Bipolar Disorder Research Network. Bipolar Disorders22(7), 731–738. https://doi.org/10.1111/bdi.12905

Gordon-Smith, K., Perry, A., Di Florio, A., Forty, L., Fraser, C., Casanova Dias, M., Warne, N., MacDonald, T., Craddock, N., Jones, L., & Jones, I. (2020). Symptom profile of postpartum and non-postpartum manic episodes in bipolar I disorder: a within-subjects study. Psychiatry research284, 112748. https://doi.org/10.1016/j.psychres.2020.112748

Hagenaars, S. P., Coleman, J. R. I., Choi, S. W., Gaspar, H., Adams, M. J., Howard, D. M., Hodgson, K., Traylor, M., Air, T. M., Andlauer, T. F. M., Arolt, V., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Campbell, A., Cearns, M., Czamara, D., Dannlowski, U., … Lewis, C. M. (2020). Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics183(6), 309–330. https://doi.org/10.1002/ajmg.b.32807

Hodgson, K., Coleman, J. R. I., Hagenaars, S. P., Purves, K. L., Glanville, K., Choi, S. W., O’Reilly, P., Breen, G., & Lewis, C. M. (2020). Cannabis use, depression and self-harm: phenotypic and genetic relationships. Addiction115(3), 482–492. https://doi.org/10.1111/add.14845

Marwaha, S., Briley, P. M., Perry, A., Rankin, P., Diflorio, A., Craddock, N., Jones, I., Broome, M., Gordon-Smith, K., & Jones, L. (2020). Explaining why childhood abuse is a risk factor for poorer clinical course in bipolar disorder: A path analysis of 923 people with bipolar i disorder. Psychological Medicine50(14), 2346–2354. https://doi.org/10.1017/S0033291719002411

Perry, A., Gordon-Smith, K., di Florio, A., Fraser, C., Craddock, N., Jones, L., & Jones, I. (2020). Adverse childhood experiences and postpartum depression in bipolar disorder. Journal of Affective Disorders263, 661–666. https://doi.org/10.1016/j.jad.2019.11.042

Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. K., McIntosh, A. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F., … Whalley, H. C. (2020). A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank. Nature Communications11(1). https://doi.org/10.1038/s41467-020-16022-0

Soda, T., McLoughlin, D. M., Clark, S. R., Oltedal, L., Kessler, U., Haavik, J., Bousman, C., Smith, D. J., Bioque, M., Clements, C. C., Loo, C., Vila-Rodriguez, F., Minelli, A., Mickey, B. J., Milev, R., Docherty, A. R., Langan Martin, J., Achtyes, E. D., Arolt, V., … Baune, B. T. (2020). International Consortium on the Genetics of Electroconvulsive Therapy and Severe Depressive Disorders (Gen-ECT-ic). European Archives of Psychiatry and Clinical Neuroscience270(7), 921–932. https://doi.org/10.1007/s00406-019-01087-w

2019


Arnau-Soler, A., Macdonald-Dunlop, E., Adams, M. J., Clarke, T. K., MacIntyre, D. J., Milburn, K., Navrady, L., Hayward, C., McIntosh, A. M., & Thomson, P. A. (2019). Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland. Translational Psychiatry9(1). https://doi.org/10.1038/s41398-018-0360-y

Charney, A. W., Stahl, E. A., Green, E. K., Chen, C. Y., Moran, J. L., Chambert, K., Belliveau, R. A., Forty, L., Gordon-Smith, K., Lee, P. H., Bromet, E. J., Buckley, P. F., Escamilla, M. A., Fanous, A. H., Fochtmann, L. J., Lehrer, D. S., Malaspina, D., Marder, S. R., Morley, C. P., … Sklar, P. (2019). Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases. Biological Psychiatry86(2), 110–119. https://doi.org/10.1016/j.biopsych.2018.12.009

Drange, O. K., Bjerkehagen Smeland, O., Shadrin, A. A., Finseth, P. I., Witoelar, A., Frei, O., Wang, Y., Hassani, S., Djurovic, S., Dale, A. M., & Andreassen, O. A. (2019). Genetic overlap between alzheimer’s disease and bipolar disorder implicates the MARK2 and VAC14 genes. Frontiers in Neuroscience13, 220. https://doi.org/10.3389/fnins.2019.00220

Foo, J. C., Streit, F., Frank, J., Witt, S. H., Treutlein, J., Baune, B. T., Moebus, S., Jöckel, K. H., Forstner, A. J., Nöthen, M. M., Rietschel, M., Sartorius, A., & Kranaster, L. (2019). Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics180(1), 35–45. https://doi.org/10.1002/ajmg.b.32700

Gerring, Z. F., Gamazon, E. R., & Derks, E. M. (2019). A gene co-expression network-based analysis of multiple brain tissues reveals novel genes and molecular pathways underlying major depression. PLoS Genetics15(7). https://doi.org/10.1371/journal.pgen.1008245

Gordon-Smith, K., Saunders, K., Geddes, J. R., Harrison, P. J., Hinds, C., Craddock, N., Jones, I., & Jones, L. (2019). Large-scale roll out of electronic longitudinal mood-monitoring for research in affective disorders: Report from the UK bipolar disorder research network. Journal of Affective Disorders246, 789–793. https://doi.org/10.1016/j.jad.2018.12.099

Hübel, C., Gaspar, H. A., Coleman, J. R. I., Hanscombe, K. B., Purves, K., Prokopenko, I., Graff, M., Ngwa, J. S., Workalemahu, T., O’Reilly, P. F., Bulik, C. M., & Breen, G. (2019). Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent. Nature Communications10(1). https://doi.org/10.1038/s41467-019-13544-0

Lee, P. H., Anttila, V., Won, H., Feng, Y. C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., Wang, M. M. J., Yu, D., Stahl, E. A., Walters, R. K., Anney, R. J. L., Duncan, L. E., Ge, T., Adolfsson, R., Banaschewski, T., … Smoller, J. W. (2019). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell179(7), 1469-1482.e11. https://doi.org/10.1016/j.cell.2019.11.020

Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Andreassen, O., Pedersen, C. B., Pedersen, M. G., Mors, O., Nordentoft, M., Børglum, A. D., Werge, T., & Agerbo, E. (2019). Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia with Risk for Depression in the Danish Population. JAMA Psychiatry76(5), 516–525. https://doi.org/10.1001/jamapsychiatry.2018.4166

Perry, A., Gordon-Smith, K., Webb, I., Fone, E., di Florio, A., Craddock, N., Jones, I., & Jones, L. (2019). Postpartum psychosis in bipolar disorder: no evidence of association with personality traits, cognitive style or affective temperaments. BMC Psychiatry19(1), 395. https://doi.org/10.1186/s12888-019-2392-0

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Agrawal, A., Borglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R., Sullivan, P. F., … Polderman, T. J. C. (2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls. Psychological Medicine49(7), 1166–1173. https://doi.org/10.1017/S0033291718002039

Polimanti, R., Peterson, R. E., Ong, J. S., MacGregor, S., Edwards, A. C., Clarke, T. K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., Maes, H. H., Martin, N. G., Mbarek, H., Medland, S. E., Streit, F., Agrawal, A., Edenberg, H. J., Kendler, K. S., Lewis, C. M., … Derks, E. M. (2019). Evidence of causal effect of major depression on alcohol dependence: Findings from the psychiatric genomics consortium. Psychological Medicine49(7), 1218–1226. https://doi.org/10.1017/S0033291719000667

Serra, F., Gordon-Smith, K., Perry, A., Fraser, C., di Florio, A., Craddock, N., Jones, I., & Jones, L. (2019). Agitated depression in bipolar disorder. Bipolar Disorders21(6), 547–555. https://doi.org/10.1111/bdi.12778

Smeeth, D. M., Dima, D., Jones, L., Jones, I., Craddock, N., Owen, M. J., Rietschel, M., Maier, W., Korszun, A., Rice, J. P., Mors, O., Preisig, M., Uher, R., Lewis, C. M., Thuret, S., & Powell, T. R. (2019). Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibility. Psychoneuroendocrinology106, 284–292. https://doi.org/10.1016/j.psyneuen.2019.04.011

Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M. W., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L., … Sklar, P. (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics51(5), 793–803. https://doi.org/10.1038/s41588-019-0397-8

Trzaskowski, M., Mehta, D., Peyrot, W. J., Hawkes, D., Davies, D., Howard, D. M., Kemper, K. E., Sidorenko, J., Maier, R., Ripke, S., Mattheisen, M., Baune, B. T., Grabe, H. J., Heath, A. C., Jones, L., Jones, I., Madden, P. A. F., McIntosh, A. M., Breen, G., … Wray, N. R. (2019). Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics180(6), 439–447. https://doi.org/10.1002/ajmg.b.32713

Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., … Levinson, D. F. (2019). Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts. Biological Psychiatry85(12), 1065–1073. https://doi.org/10.1016/j.biopsych.2019.02.022

2018


Allardyce, J., Leonenko, G., Hamshere, M., Pardiñas, A. F., Forty, L., Knott, S., Gordon-Smith, K., Porteous, D. J., Haywood, C., di Florio, A., Jones, L., McIntosh, A. M., Owen, M. J., Holmans, P., Walters, J. T. R., Craddock, N., Jones, I., O’Donovan, M. C., & Escott-Price, V. (2018). Association between schizophrenia-related polygenic liability and the occurrence and level of mood-incongruent psychotic symptoms in bipolar disorder. JAMA Psychiatry, 75(1), 28–35. https://doi.org/10.1001/jamapsychiatry.2017.3485

di Florio, A., Gordon-Smith, K., Forty, L., Kosorok, M. R., Fraser, C., Perry, A., Bethell, A., Craddock, N., Jones, L., & Jones, I. (2018). Stratification of the risk of bipolar disorder recurrences in pregnancy and postpartum. British Journal of Psychiatry, 213(3), 542–547. https://doi.org/10.1192/bjp.2018.92

Foo, J. C., Streit, F., Treutlein, J., Ripke, S., Witt, S. H., Strohmaier, J., Degenhardt, F., Forstner, A. J., Hoffmann, P., Soyka, M., Dahmen, N., Scherbaum, N., Wodarz, N., Heilmann-Heimbach, S., Herms, S., Cichon, S., Preuss, U., Gaebel, W., Ridinger, M., … Frank, J. (2018). Shared genetic etiology between alcohol dependence and major depressive disorder. Psychiatric Genetics, 28(4), 66–70. https://doi.org/10.1097/YPG.0000000000000201

Lewis, K. J. S., di Florio, A., Forty, L., Gordon-Smith, K., Perry, A., Craddock, N., Jones, L., & Jones, I. (2018). Mania triggered by sleep loss and risk of postpartum psychosis in women with bipolar disorder. Journal of Affective Disorders, 225, 624–629. https://doi.org/10.1016/j.jad.2017.08.054

Maaser, A., Forstner, A. J., Strohmaier, J., Hecker, J., Ludwig, K. U., Sivalingam, S., Streit, F., Degenhardt, F., Witt, S. H., Reinbold, C. S., Koller, A. C., Raff, R., Heilmann-Heimbach, S., Fischer, S. B., Herms, S., Hoffmann, P., Thiele, H., Nürnberg, P., Fier, H. L., … Nöthen, M. M. (2018). Exome sequencing in large, multiplex bipolar disorder families from Cuba. PLoS ONE, 13(10). https://doi.org/10.1371/journal.pone.0205895

Roberts, L., Berrisford, G., Heron, J., Jones, L., Jones, I., Dolman, C., & Lane, D. A. (2018). Qualitative exploration of the effect of a television soap opera storyline on women with experience of postpartum psychosis. BJPsych Open, 4(2), 75–82. https://doi.org/10.1192/bjo.2018.9

Ruderfer, D. M., Ripke, S., McQuillin, A., Boocock, J., Stahl, E. A., Pavlides, J. M. W., Mullins, N., Charney, A. W., Ori, A. P. S., Loohuis, L. M. O., Domenici, E., di Florio, A., Papiol, S., Kalman, J. L., Trubetskoy, V., Adolfsson, R., Agartz, I., Agerbo, E., Akil, H., … Kendler, K. S. (2018). Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell, 173(7), 1705-1715.e16. https://doi.org/10.1016/j.cell.2018.05.046

Trautmann, N., Foo, J. C., Frank, J., Witt, S. H., Streit, F., Treutlein, J., von Heydendorff, S. C., Gilles, M., Forstner, A. J., Ebner-Priemer, U., Nöthen, M. M., Deuschle, M., & Rietschel, M. (2018). Response to therapeutic sleep deprivation: a naturalistic study of clinical and genetic factors and post-treatment depressive symptom trajectory. Neuropsychopharmacology, 43(13), 2572–2577. https://doi.org/10.1038/s41386-018-0092-y

2017


Green EK, Di Florio A, Forty L, Gordon-Smith K, Grozeva D, Fraser C, et al. Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type. Am J Med Genet Part B Neuropsychiatr Genet 2017; 174: 767–71.

Lewis KS, Gordon-Smith K, Forty L, Di Florio A, Craddock N, Jones L, et al. Sleep loss as a trigger of mood episodes in bipolar disorder : individual differences based on diagnostic subtype and gender. British Journal of Psychiatry 2017; 211: 169–74.

Gordon-Smith K, Jones L, Forty L, Craddock N, Jones I. Changes to the Diagnostic Criteria for Bipolar Disorder in DSM-5 Make Little Difference to Lifetime Diagnosis: Findings from the UK BDRN Study. American Journal of Psychiatry 2017; 174: 803.

Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, et al. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Translational Psychiatry 2017; 7: e1155.

Perry A, Gordon-Smith K, Jones L, Jones I. A visual timeline tool for tracking mood and medication perinatally in affective disorders. Archives of Womens Mental Health 2017; 20: 709–10.

van Hulzen KJE, Scholz CJ, Franke B, Ripke S, Klein M, McQuillin A, et al. Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis. Biological Psychiatry 2017; 82: 634–41.

Charney AW, Ruderfer DM, Stahl EA, Moran JL, Chambert K, Belliveau RA, et al. Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Translational Psychiatry 2017; 7: e993.

Ahmad Abu-Akel, Jennifer Clark, Amy Perry, Stephen J. Wood, Liz Forty, Nick Craddock, Ian Jones, Katherine Gordon-Smith, Lisa Jones. Autistic and Schizotypal Traits and Global Functioning in Bipolar Disorder.  Journal of Affective Disorders. 2017; 207:268-275.

2016


S. Marwaha, K. Gordon-Smith, M. Broome, P.M. Briley, A. Perry, L. Forty, N. Craddock, I. Jones, L. Jones. Affective instability, childhood trauma and major affective disorders. Journal of Affective Disorders. 2016; 190:764-771.


Amy Perry, Katherine Gordon-Smith, Arianna Di Florio, Liz Forty, Nick Craddock, Lisa Jones, and Ian Jones. Adverse childhood life events and postpartum psychosis in bipolar disorder. Journal of Affective Disorders. 2016; 205:69-72


Jie Song, Sarah E. Bergen, Arianna Di Florio, Robert Karlsson, Alexander Charney, Douglas M. Ruderfer, Eli A. Stahl, The International Cohort Collection for Bipolar Disorder (ICCBD), Kimberly D. Chambert, Jennifer L. Moran, Katherine Gordon-Smith, Liz Forty, Elaine K. Green, Ian Jones, Lisa Jones, Edward M. Scolnick, Pamela Sklar, Jordan W. Smoller, Paul Lichtenstein, Christina Hultman, Nicholas Craddock, Mikael Landén. Genome-wide association study identifies SESTD1 as a novel risk gene for lithium responsive bipolar disorder. Molecular Psychiatry. 2016; 21(9):1290-7


MullinsR. A. Power, H. L. FisherK. B. HanscombeJ. EuesdenR. IniestaD. F. LevinsonM. M. WeissmanJ. B. PotashJ. ShiR. UherS. Cohen-WoodsM. RiveraL. JonesI. JonesN. CraddockM. J. OwenA. KorszunI. W. CraigA. E. FarmerP. McGuffinG. Breenand C. M. Lewis. Polygenic interactions with environmental adversity in the aetiology of major depressive disorder. Psychol Med. 2016; 46(4):759-70.


James J.H. Rucker, Katherine E. Tansey, Inti Pedroso, Margarita Rivera, Dalila Pinto, Cathryn M. Lewis, Sarah Cohen-Woods, Rudolf Uher, Katherine J. Aitchison, Nick Craddock, Michael J. Owen, Lisa Jones, Ian Jones, Ania Korszun, Pierandrea Muglia, Michael R. Barnes, Martin Preisig, Ole Mors, Mike Gill, Wolfgang Maier, John Rice, Marcella Rietschel, Florian Holsboer, Anne E. Farmer, Ian W. Craig, Stephen W. Scherer, Peter McGuffin, Gerome Breen. Phenotypic Association Analyses With Copy Number Variation In Recurrent Depressive Disorder. Biological Psychiatry. 2016 ;79(4):329-36


Elaine K Green, Elliott Rees, James Walters, Katherine-Gordon Smith, Liz Forty, Detelina Grozeva, Jennifer Moran, Pamela Sklar, Stephan Ripke, Kimberly Chambert, Giulio Genovese, Steven McCarroll, Ian Jones, Lisa Jones, Michael J Owen, Michael C O’Donovan, Nick Craddock, George Kirov. Copy number variation in bipolar disorder. Molecular Psychiatry. 2016 ;21(1):89-93


2015

Di Florio, Arianna; Morgan, Holly; Jones, Lisa; Forty, Liz; Gordon-Smith, Katherine; Craddock, Nick; Jones, Ian. Smoking and postpartum psychosis. Bipolar Disorders. 2015; 17(5):572-3.


Sukhmeet Singh, Liz Forty, Arianna di Florio, Katherine Gordon-Smith, Ian Jones, Nick Craddock, Lisa Jones, Daniel J. Smith. Affective temperaments and comorbid alcohol use disorders in bipolar disorder. Journal of Affective Disorders. 2015; 186:226-31.


Lisa Jones, Alice Metcalf, Katherine Gordon-Smith, Liz Forty, Amy Perry, Joanne Lloyd, John R Geddes, Guy M Goodwin, Ian Jones, Nick Craddock, Robert D Rogers. The prevalence and distribution of gambling problems in bipolar disorder in the United Kingdom. British Journal of Psychiatry. 2015; 207:328-333.


Major Depressive Working Group of the Psychiatric Genomics Consortium. The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects. Molecular Psychiatry. 2015; 20(6):735-43.


International Cohort Collection for Bipolar Disorder Consortium. Validation of electronic health record phenotyping of bipolar disorder cases and controls. American Journal of Psychiatry. 2015; 172(4):363-72.


Major Depressive Working Group of the Psychiatric Genomics Consortium. Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder. Journal of Clinical Psychiatry. 2015; 76(2):128-34.


Major Depressive Working Group of the Psychiatric Genomics Consortium. Genetic differences in the immediate transcriptome response to stress predict risk-related brain function and psychiatric disorders. Neuron. 2015; 86(5):1189-202.


Network and Pathway Analysis Subgroup of Psychiatric Genomics Consortium. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature Neuroscience. 2015; 18(2):199-209.


Panagiotis Ferentinos, Artemis Koukounari, Robert Power, Margarita Rivera, Rudolf Uher, Nicholas Craddock, Michael J. Owen, Ania Korszun, Lisa Jones, Ian Jones, Michael Gill, John P. Rice, Marcus Ising, Wolfgang Maier, Ole Mors, Marcella Rietschel, Martin Preisig, Elisabeth B. Binder, Kathy Aitchison, Julien Mendlewicz, Daniel Souery, Joanna Hauser, Neven Henigsberg, Gerome Breen, Ian W. Craig, Anne E. Farmer, Bertram Müller-Myhsok, Peter McGuffin, Cathryn M. Lewis. Familiality and SNP-heritability of age at onset and episodicity in major depressive disorder. Psychological Medicine. 2015; 45910:2215-2225.


Chi-Fa Hung, Gerome Breen, Darina Czamara, Tanguy Corre, Christiane Wolf, Stefan Kloiber, Sven Bergmann, Nick Craddock, Michael Gill, Florian Holsboer, Lisa Jones, Ian Jones, Ania Korszun, Zoltan Kutalik, Susanne Lucae, Wolfgang Maier, Ole Mors, Michael J Owen, John Rice, Marcella Rietschel, Rudolf Uher, Peter Vollenweider, Gerard Waeber, Ian W. Craig, Anne E. Farmer, Cathryn M. Lewis, Bertram Müller-Myhsok, Martin Preisig, Peter McGuffin, Margarita Rivera. A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder. BMC Medicine. 2015; 13:86


Cross-Disorder Working Group of the Psychiatric Genomics Consortium. Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. American Journal of Human Genetics. 2015; 96(2): 283-94.


Rachel Upthegrove, Christine Chard, Lisa Jones, Katherine Gordon-Smith, Liz Forty, Ian Jones, Nick Craddock. Adverse Childhood Events and Psychosis in Bipolar Affective Disorder. British Journal of Psychiatry. 2015; 206: 191-7.


Gordon-Smith, L. Forty, C. Chan, I. Jones, N. Craddock, L.A. Jones. Rapid cycling as a feature of bipolar disorder and comorbid migraine. Journal of Affective Disorders. 2015: 175, 320-324.


Arianna Di Florio, Lisa Jones, Liz Forty, Katherine Gordon-Smith, Nick Craddock, Ian Jones. Bipolar disorder, miscarriage and termination. Bipolar Disorders. 2015; 17: 102-105.


2014

Rees E, Kirov G, Sanders A, Walters JT, Chambert KD, Shi J, Szatkiewicz J, O’Dushlaine C, Richards AL, Green EK, Jones I, Davies G, Legge SE, Moran JL, Pato C, Pato M, Genovese G, Levinson D, Duan J, Moy W, Göring HH, Morris D, Cormican P, Kendler KS, O’Neill FA, Riley B, Gill M, Corvin A; Wellcome Trust Case Control Consortium, Craddock N, Sklar P, Hultman C, Sullivan PF, Gejman PV, McCarroll SA, O’Donovan MC, Owen MJ. Evidence that duplications of 22q11.2 protect against schizophrenia. Molecular Psychiatry. 2014; 9(1):37-40.


Liz Forty, Anna Ulanova, Lisa Jones, Ian Jones, Katherine Gordon-Smith, Christine Fraser, Anne Farmer, Peter McGuffin, Cathryn Lewis, Georgina Hosang, Nick Craddock. Comorbid Medical Illness in Bipolar Disorder. British Journal of Psychiatry. 2014; 205 (6): 465-472.


Chi-Fa Hung, Margarita Rivera, Nick Craddock, Michael J. Owen, Michael Gill, Ania Korszun, Wolfgang Maier, Ole Mors, Martin Preisig, John P. Rice, Marcella Rietschel, Lisa Jones, Lefkos Middleton, Kathy J Aitchison, Oliver S.P Davis, Gerome Breen, Cathryn Lewis, Anne Farmer, Peter McGuffin. Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study. British Journal of Psychiatry. 2014; 205(1): 24-28.


Psychiatric Genomics Consortium Bipolar Group. Identification of pathways for bipolar disorder: a meta-analysis. JAMA Psychiatry. 2014; 71(6):657-64.


Niamh Mullins, Nader Perroud, Rudolf Uher, Amy W. Butler, Sarah Cohen-Woods, Margarita Rivera, Karim Malki, Jack Euesden, Katherine E. Tansey, Lisa Jones, Ian Jones, Nick Craddock, Michael J. Owen, Ania Korszun, Michael Gill, Ole Mors, Martin Preisig, Wolfgang Maier, Marcella Rietschel, John P. Rice, Bertram Müller-Myhsok, Federica Tozzi, Elisabeth B. Binder, Susanne Lucae, Pierandrea Muglia, Marcus Ising, Ian W. Craig, Anne E. Farmer, Peter McGuffin, Gerome Breen, Cathryn M. Lewis. Genetic Relationships between Suicide Attempts, Suicidal Ideation and Major Psychiatric Disorders: a Genome-wide Association and Polygenic Scoring Study. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 2014: 165B(5), 428-437.


Helen Court, Liz Forty, Lisa Jones, Katherine Gordon-Smith, Ian Jones, Nick Craddock, Daniel J. Smith. Improving the psychometric utility of the Hypomania Checklist (HCL-32): a Rasch analysis approach. Journal of Affective Disorders, 2014: 152-154, 448-453.


Di Florio A, Craddock N, van den Bree M. Alcohol misuse in bipolar disorder. A systematic review and meta-analysis of comorbidity rates. European Psychiatry. 2014; 29(3):117-24.


Cross-Disorder Working Group of Psychiatric Genomics Consortium. Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia. Molecular Psychiatry. 2014; 19(9): 1017-24.


Psychiatric Genomics Consortium Bipolar Group. Identification of pathways for bipolar disorder: a meta-analysis. JAMA Psychiatry. 2014; 71(6): 657-64.


Panagiotis Ferentinos, Margarita Rivera, Marcus Ising, Sarah Spain, Sarah Cohen-Woods, Amy W. Butler, Nicholas Craddock, Michael J. Owen, Ania Korszun, Lisa Jones, Ian Jones, Michael Gill, John P. Rice, Wolfgang Maier, Ole Mors, Marcella Rietschel, Susanne Lucae, Elisabeth B. Binder, Martin Preisig, Julia Perry, Federica Tozzi, Pierandrea Muglia, Gerome Breen, Ian W. Craig, Anne E. Farmer, Bertram Müller-Myhsok, Peter McGuffin, Cathryn M. Lewis. Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution. Journal of Affective Disorders, 2014: 155, 81-89.


Arianna Di Florio, Lisa Jones, Liz Forty, Katherine Gordon-Smith, Jess Heron, Trine Munk-Olsen, Nick Craddock, Ian Jones. Perinatal mood disorders and parity – a clue to the aetiology of the postpartum trigger. Journal of Affective Disorders, 2014: 152-154, 334-339.


2013

Hamshere ML, Walters JT, Smith R, Richards AL, Green E, Grozeva D, Jones I, Forty L, Jones L, Gordon-Smith K, Riley B, O’Neill FA, Kendler KS, Sklar P, Purcell S, Kranz J; Schizophrenia Psychiatric Genome-wide Association Study Consortium; Wellcome Trust Case Control Consortium+; Wellcome Trust Case Control Consortium 2, Morris D, Gill M, Holmans P, Craddock N, Corvin A, Owen MJ, O’Donovan MC. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Molecular Psychiatry. 2013: 18(6), 708-12.


E K Green, D Grozeva, L Forty, K Gordon-Smith, Russell E, A Farmer, I R Jones, L Jones, P McGuffin, J L Moran, J E Kranz, Purcell S, P Sklar, M J Owen, M C O’Donovan, N Craddock. Association at SYNE1 in both Bipolar Disorder and Recurrent Major Depression. Molecular Psychiatry. 2013: 18(5), 614-617.


Elaine K Green, Marian Hamshere, Liz Forty, Katherine Gordon-Smith, Christine Fraser, Elen Russell, Detelina Grozeva, George Kirov, Peter Holmans, Jennifer L Moran, Shaun Purcell, Pamela Sklar, Michael J Owen, Michael C O’Donovan, Lisa Jones, WTCCC, Ian R Jones, Nick Craddock. Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. Molecular Psychiatry, 2013: 18, 1302-1307.


Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet, 2013: 381(9875), 1371-9.


Cross-Disorder Group of the Psychiatric Genomics Consortium. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics, 2013: 45(9), 984-94.


James J.H. Rucker, Gerome Breen, Dalila Pinto, Inti Pedroso, Cathryn M. Lewis, Sarah Cohen-Woods, Rudolf Uher, Alexandra Schosser, Margarita Rivera, Katherine J. Aitchison, Nick Craddock, Michael J. Owen, Lisa Jones, Ian Jones, Ania Korszun, Pierandrea Muglia, Michael R. Barnes, Martin Preisig, Ole Mors, Mike Gill, Wolfgang Maier, John Rice, Marcella Rietschel, Florian Holsboer, Anne E. Farmer, Ian W. Craig, Stephen W. Scherer, Peter McGuffin. Genome-wide association analysis of copy number variation in recurrent depressive disorder. Molecular Psychiatry, 2013: 18(2), 183-189.


Di Florio A, Forty L, Gordon-Smith K, Heron J, Jones L, Craddock N, Jones I. Perinatal episodes across the mood disorder spectrum. JAMA Psychiatry, 2013: 70(2), 168-175.


Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium. A Mega-Analysis of Genome-Wide Association Studies for Major Depressive Disorder. Molecular Psychiatry, 2013: 18(4), 497-511.


Robert A. Power, Sarah Cohen-Woods, Mandy Y. Ng, Amy W. Butler, Nick Craddock, Michael J. Owen, Ania Korszun, Lisa Jones, Ian Jones, Michael Gill, John P. Rice, Wolfgang Maier, Astrid Zobel, Ole Mors, Anna Placentino, Marcella Rietschel, Katherine J. Aitchison, Federica Tozzi, Pierandrea Muglia, Gerome Breen, Ian W. Craig, Anne E. Farmer, Peter McGuffin, Cathryn M. Lewis, Rudolf Uher. Genome-wide association analysis accounting for environmental factors through propensity-score matching: application to stressful live events in major depressive disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 2013: 162B(6), 521-9.


Robert A. Power, Lucy Lecky- Thompson, Helen L. Fisher, Sarah Cohen-Woods, Georgina M. Hosang, Rudolf Uher, Georgia Powell-Smith, Robert Keers, Maria Tropeano, Ania Korszun, Lisa Jones, Ian Jones, Mike Owen, Nick Craddock, Ian W. Craig, Anne E. Farmer, Peter McGuffin. The interaction between child maltreatment, adult stressful life events and the 5-HTTLPR polymorphism in major depression. Journal of Psychiatric Research, 2013: 47(8), 1032-5.


Corin Bourne, Ömer Aydemir, Vicente Balanzá-Martínez, Emre Bora, Sofia Brissos, Jonathan T. O. Cavanagh, Luke Clark, Zeynep Cubukcuoglu, Vasco Videira Dias, Sandra Dittman, I. Nicol Ferrier, David E. Fleck, Sophia Frangou, Peter Gallagher, Lisa Jones, Tuula Kieseppä, Anabel Martínez-Aran, Ingrid Melle, P. Brain Moore, Maria Mur, Andrea Pfenning, Aurélie Raust, Vesile Senturk, Carmen Simonsen, Daniel J. Smith, Danielle Soares Bio, Marcio Gerhardt Soeiro-de-Souza, Samuel D. R. Stoddart, Kjetil Sundet, Andrei Szöke, Jill M. Thompson, Carla Torrent, Tiziana Zalla, Nick Craddock, Ole A Andreassen, Marion Leboyer, Eduard Vieta, Michael Bauer, Patrick Worhunsky, Charidimos Tzagarakis, Robert D. Rogers, John R. Geddes, Guy M. Goodwin. Neuropsychological Testing of Cognitive Impairment in Euthymic Bipolar Disorder: An individual patient data meta-analysis. Acta Psychiatrica Scandanavica, 2013: 128(3), 149-62.


Power RA, Wingenbach T, Cohen-Woods S, Uher R, Ng MY, Butler AW, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Zobel A, Mors O, Placentino A, Rietschel M, Lucae S, Holsboer F, Binder EB, Keers R, Tozzi F, Muglia P, Breen G, Craig IW, Müller-Myhsok B, Kennedy JL, Strauss J, Vincent JB, Lewis CM, Farmer AE, McGuffin P. Estimating the heritability of reporting stressful life events captured by common genetic variants. Psychological Medicine, 2013: 43(9), 1965-71.


2012

Georgina M. Hosang, Ania Korszun, Lisa Jones, Ian Jones, Peter McGuffin, Anne E. Farmer. Life event specificity: bipolar disorder compared to unipolar depression. British Journal of Psychiatry, 2012: 201(6), 458-65.


Robert A. Power, Robert Keers, Mandy Y. Ng, Amy W. Butler, Rudolf Uher, Sarah Cohen-Woods, Marcus Ising, Nicholas Craddock, Michael J. Owen, Ania Korszun, Lisa Jones, Ian Jones, Michael Gill, John P. Rice, Joanna Hauser, Neven Henigsberg, Wolfgang Maier, Astrid Zobel, Ole Mors, Anna S. Placentino, Marcella Rietschel, Daniel Souery, Dejan Kozel, Martin Preisig, Julia Perry, Susanne Lucae, Elisabeth B. Binder, Katherine J. Aitchison, Federica Tozzi, Pierandrea Muglia, Gerome Breen, Ian W. Craig, Anne E. Farmer, Bertram Muller-Myhsok, Peter McGuffin, and Cathryn M. Lewis. Dissecting the genetic heterogeneity of depression through age-of-onset. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 2012: 59B(7), 859-68.


Doyle, J. Heron, G. Berrisford, J Whitmore, G. Wainscott, L. Jones, F. Oyebode. The management of bipolar disorder in the perinatal period and risk factors for postpartum relapse. European Psychiatry, 2012: 27(8), 563-569.


Helen L. Fisher, Sarah Cohen-Woods, Georgina M. Hosang, Rudolf Uher, Georgia Powell-Smith, Robert Keers, Maria Tropeano, Ania Korszun, Lisa Jones, Ian Jones, Mike Owen, Nick Craddock, Ian W. Craig, Anne E. Farmer, Peter McGuffin. Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depression.   Journal of Affective Disorders, 2012: 136; 189-193.


Badner JA, Koller D, Foroud T, Edenberg H, Nurnberger JI Jr, Zandi PP, Willour VL, McMahon FJ, Potash JB, Hamshere M, Grozeva D, Green E, Kirov G, Jones I, Jones L, Craddock N, Morris D, Segurado R, Gill M, Sadovnick D, Remick R, Keck P, Kelsoe J, Ayub M, MacLean A, Blackwood D, Liu CY, Gershon ES, McMahon W, Lyon GJ, Robinson R, Ross J, Byerley W. Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms. Molecular Psychiatry, 2012: 17(8); 818-826.


2011

Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nature Genetics, 2011: 43(10); 977-83.


Gerome Breen, Bradley Todd Webb, Amy Butler, Edwin JCG van den Oord, Federica Tozzi, Nick Craddock, Mike Gill, Ania Korszun, Wolfgang Maier, Lefkos Middleton, Florian Holsboer, Ole Mors, Susanne Lucae, Michael J. Owen, Julia Perry, Ian Craig, Cathryn M. Lewis, Mandy Ng, Shyama Brewster, Martin Preisig, John Rice, Marcella Rietschel, Lisa Jones, Jo Knight, Pierandrea Muglia, Anne E. Farmer, Peter McGuffin. A genomewide significant linkage for severe depression on chromosome 3: the Depression Network Study. American Journal of Psychiatry, 2011: 168(8); 840-847.


Schosser A, Gaysina D, Cohen-Woods S, Domenici E, Perry J, Tozzi F, Korszun A, Gunasinghe C, Gray J, Jones L, Binder E, Holsboer F, Craddock N, Owen MJ, Craig IW, Farmer AE, Muglia P, McGuffin P A follow-up case-control association study of tractable (druggable) genes in recurrent major depression. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 2011: 156B(6):640-650.


Sarah Dwyer, Hywel Williams, Ian Jones, Lisa Jones, James Walters, Nick Craddock, Michael J Owen, Michael C O’Donovan. Investigation of rare nonsynonymous variants at ABCA13 in schizophrenia and bipolar disorder. Molecular Psychiatry, 2011; 16(8); 790-791.


Liu Y, Blackwood DH, Caesar S, de Geus EJC, Farmer A, Ferreira MAR, Ferrier IN, Fraser C, Gordon-Smith K, Green EK, Grozeva D, Gurling HM, Hamshere ML, Heutink P, Holmans PA, Hoogendijk WJ, Hottenga JJ, Jones L, Jones IR, Kirov G, Lin DY, McGuffin P, Moskvina V, Nolen WA, Perlis RH, Posthuma D, Scolnick EM, Smit AB, Smit JH, Smoller JW, St. Clair D, van Dyck R, Verhage M, Wellcome Trust Case-Control Consortium, Willemsen G, Young AH, Zandbelt T, Boomsma DI, Craddock N, O’Donovan MC, Owen MJ, Penninx BWJH, Purcell S, Sklar P, Sullivan P. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Molecular Psychiatry, 2011: 16(1); 2-4.


E K Green, D Grozeva, R Sims, R Raybould, L Forty, K Gordon-Smith, E Russell, D St. Clair, AH Young, IN Ferrier, G Kirov, I Jones, L Jones, M Owen, M O’Donovan, N Craddock. DISC1 exon 11 rare variants found more commonly in schizoaffective spectrum cases than controls. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 2011: 156B (4); 490-492.


Schosser A, Butler AW, Ising M, Perroud N, Uher R, Ng MY, Cohen-Woods S, Craddock N, Owen M, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Mors O, Rietschel M, Lucae S, Binder ED, Preisig M, Perry J, Tozzi F, Muglia P, Aitchison KJ, Breen G, Craig I, Farmer AE, Müller-Myhsok, B, McGuffin P, Lewis CM. Genome wide association scan of suicidal thoughts and behaviour in major depression. PLoS ONE, 2011: 6(7), e20690.


M L Hamshere, M C O’Donovan, I R Jones, L Jones, G Kirov, E K Green, V Moskvina, D Grozeva, N Bass, A McQuillin, H Gurling, D St Clair, A H Young, I N Ferrier, A Farmer, P McGuffin, P. Sklar, S. Purcell, P A Holmans, M J Owen, N Craddock. Polygenic dissection of the bipolar phenotype. British Journal of Psychiatry, 2011: 198; 284-288.


2010

Butler AW, Breen G, Federica Tozzi, Nick Craddock, Mike Gill, Ania Korszun, Wolfgang Maier, Lefkos Middleton, Ole Mors, Michael J. Owen, Julia Perry, Martin Preisig, John P. Rice, Marcella Rietschel, Lisa Jones, Farmer AE, Lewis CM, McGuffin P. A genome-wide linkage study on suicidality in major depressive disorder confirms evidence for linkage to 2p12. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 2010: 158(8); 1465-1473.


Elaine K Green, Detelina Grozeva, Valentina Moskvina, Marian L Hamshere, Ian R Jones, Lisa Jones, Sian Caesar, Katherine Gordon-Smith, Christine Fraser, Ellie Russell, David St Clair, Allan H Young, Nicol Ferrier, Anne Farmer, Peter McGuffin, Peter A Holmans, Mike J Owen, Mick C O’Donovan, Nick Craddock. Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 2010: 153(7); 1347-1349.


Cohen-Woods S, Craig I, Gaysina D, Gray J, Gunasinghe C, Craddock N, Elkin A, Jones L, Kennedy J, King N, Korszun A, Knight J, Owen M, Parikh S, Strauss J, Sterne A, Tozzi F, Perry J, Muglia P, Vincent J, McGuffin P, Farmer A. The bipolar association case control study (BACCS) and meta-analysis: No association with the 5,10-methylenetetrahydrofolate reductase gene and bipolar disorder. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, 2010: 153(7); 1298-1304.


Georgina M. Hosang, Ania Korszun, Lisa Jones, Ian Jones, Joanna M. Gray, Cerisse M. Gunasinghe, Peter McGuffin, Anne E. Farmer. Adverse event reporting and worst illness episodes in unipolar and bipolar affective disorder: Measuring environmental risk for genetic research. Psychological Medicine, 2010: 40(11); 1829-1837.


Schosser A, Gaysina D, Cohen-Woods S, Chow PC, Martucci L, Craddock N, Farmer A, Korszun A, Gunasinghe C, Gray J, Jones L, Federica Tozzi, Julia Perry, Pierandrea Muglia, Owen MJ, Craig IW, McGuffin P. Association of DISC1 and TSNAX genes and affective disorders in the Depression Case-Control (DeCC) and Bipolar Affective Case-Control (BACCS) studies. Molecular Psychiatry, 2010: 15(8); 844-849.

 


E K Green, D Grozeva, I R Jones, L Jones, G Kirov, S Caesar, K Gordon-Smith, C Fraser, L Forty, E Russell, M L Hamshere, V Moskvina, I Nikolov, A Farmer, P McGuffin, Wellcome Trust Case Control Consortium, P A Holmans, M J Owen, M C O’Donovan and N Craddock. Bipolar disorder risk allele at CACNA1C also confers risk to recurrent major depression and to schizophrenia. Molecular Psychiatry, 2010: 15(10); 1016-1022.


Lewis CM, Ng MY, Butler AW, Cohen-Woods S, Uher R, Pirlo K, Weale M, Schosser A, Paredes U, Rivera-Sanchez M, Craddock N, Owen MJ, Jones L, Jones I, Korszun A, Aitchison KJ, Shi J, Quinn J, McKenzie A, Heath S, Lathrop M, Muglia P, Barnes M, Whittaker JC, Tozzi F, Holsboer F, Preisig M, Farmer AE, Breen G, Craig I, McGuffin P. Genome-wide association study of major recurrent depression in the UK population. American Journal of Psychiatry, 2010: 167(8); 949-957.


Liz Forty, Mark Kelly, Lisa Jones, Ian Jones Emma Barnes, Sian Caesar, Christine Fraser, Katherine Gordon-Smith, Emily Griffiths, Nick Craddock, Daniel J Smith. Reducing the Hypomania Checklist (HCL-32) to a 16-item version. Journal of Affective Disorders, 2010: 124; 351-356.


Welcome Trust Case Control Consortium. Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 2010: 464(7289); 713-20.


D Grozeva, G Kirov, D Ivanov, I R Jones, L Jones, E K Green, D St Clair, A H Young, I N Ferrier, A Farmer, P McGuffin, Wellcome Trust Case Control Consortium, P A Holmans, M J Owen, M C O’Donovan, N Craddock. Rare copy number variants (CNVs): A point of rarity in genetic risk for bipolar disorder and schizophrenia? Archives of General Psychiatry, 2010: 67(4); 318-27.


Nick Craddock , Lisa Jones, Ian R Jones, George Kirov, Elaine K Green, Detelina Grozeva, Valentina Moskvina, Ivan Nikolov, Marian L Hamshere, Damjan Vukcevic, Sian Caesar, Katharine Gordon-Smith, Christine Fraser, Ellie Russell, Nadine Norton, Gerome Breen, David St Clair; David A Collier, Allan H Young, I Nicol Ferrier; Anne Farmer, Peter McGuffin; Peter A Holmans, Wellcome Trust Case Control Consortium (WTCCC), Peter Donnelly, Michael J Owen, Michael C O’Donovan. Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Molecular Psychiatry, 2010 15(2):146-53.


Arianna Di Florio; Marian Hamshere; Liz Forty; Elaine K Green; Detelina Grozeva; Ian Jones; Sian Caesar; Christine Fraser; Katherine Gordon-Smith; Lisa Jones; Nick Craddock; Daniel J Smith. Affective temperaments across the bipolar-unipolar spectrum: examination of the TEMPS-A in 927 patients and controls. Journal of Affective Disorders, 2010: 123; 42-51.


Lisa Jones, Jan Scott, Sian Caesar, Caroline Cooper, Liz Forty, Katherine Gordon Smith, Pak Sham, Anne Farmer, Peter McGuffin, Nick Craddock, Ian Jones. Cognitive style, personality and vulnerability to the postpartum triggering of major depression. British Journal of Psychiatry, 2010: 196; 200-205.


Schosser A, Cohen-Woods S, Gaysina D, Chow PC, Martucci L, Farmer A, Korszun A, Gunashinghe C, Gray J, Jones L, Craddock N, Owen MJ, Craig IW, McGuffin P. NRG1 gene in Recurrent Major Depression: no association in a large-scale case-control association study. American Journal of Medical Genetics (Neuropsychiatric Genetics), 2010: 153B; 141-147.


2009

Elaine K Green, Detelina Grozeva, Rachel Raybould R, Gareth Elvidge, Stuart Macgregor, Ian Craig, Anne Farmer, Peter McGuffin, Liz Forty, Lisa Jones, Jones I, Mick C O’Donovan, Mike J Owen, George Kirov, Nick Craddock. P2RX7 – a Bipolar and Unipolar Disorder candidate susceptibility gene? American Journal of Medical Genetics (Neuropsychiatric Genetics), 2009: 150B; 1063-1069.


Forty L, Smith D, Jones L, Jones I, Caesar S, Cooper C, Fraser C, Gordon-Smith K, Hyde S, Farmer A, McGuffin P, Craddock N. Clinical characteristics of unipolar disorder and bipolar disorder according to the lifetime presence of recurrent panic attacks. Bipolar Disorders, 2009: 11:307-15.


Sarah Cohen-Woods, Daria Gaysine, Nick Craddock, Anne Farmer, Joanna Gray, Cerisse Gunasinghe, Farzana Hoda, Lisa Jones, Jo Knight, Ania Korszun, Michael J Owen, Abram Sterne, Ian W Craig, Peter McGuffin. Depression Case Control (DeCC) Study fails to support involvement of the muscarinic acetylcholine receptor M2 (CHRM2) gene in recurrent major depressive disorder. Human Molecular Genetics, 2009: 18; 1504-1509.


Zainab Samaan, Anne Farmer, Nick Craddock, Lisa Jones, Ania Korszun, Michael Owen, Richard Williamson, Peter McGuffin. Migraine in recurrent depression: case-control study. British Journal of Psychiatry 2009: 194; 350-354.


Harriet A. Ball, Zainab Samaan, Shyama Brewster, Nick Craddock, Mike Gill, Ania Korszun, Wolfgang Maier, Lefkos Middleton, Ole Mors, Michael J. Owen, Julia Perry, Martin Preisig, John Rice, Marcella Rietschel, Lisa Jones, Ian Jones, Anne E. Farmer, Peter McGuffin. Depression, migraine with aura and migraine without aura: their familiality and interrelatedness. Cephalalgia 2009: 29; 848-854.


Liz Forty, Lisa Jones, Ian Jones, Carly Cooper, Elen Russell, Anne Farmer, Peter McGuffin, Nick Craddock. Is depression severity the sole cause of psychotic symptoms during an episode of unipolar major depression? A study both between and within subjects. Journal of Affective Disorders, 2009: 114;103-109.


Liz Forty, Daniel Smith, Lisa Jones, Ian Jones, Sian Caesar, Christine Fraser, Katherine Gordon-Smith, Nick Craddock. Identifying hypomanic features in major depressive disorder using the Hypomania Checklist (HCL-32). Journal of Affective Disorders, 2009: 114; 68-73.


M L Hamshere, E K Green, I R Jones, L Jones, V Moskvina, G Kirov, D Grozeva, , I Nikolov, D Vukcevic, S Caesar, K Gordon-Smith, C Fraser, E Russell, G Breen, D St Clair, D A Collier, A H Young, I N Ferrier, A Farmer, P McGuffin, Wellcome Trust Case Control Consortium, P A Holmans, M J Owen, M C O’Donovan and N Craddock. Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept. British Journal of Psychiatry, 2009: 195:23-9.


Marian L Hamshere, Thomas G Schulze, Johannes Schumacher, Aiden Corvin, Michael J Owen, Rami Abou Jamra, Peter Propping, Wolfgang Maier, Guillermo Orozco y Diaz, Fermin Mayoral, Fabio Rivas, Ian Jones, Lisa Jones, George Kirov, Michael Gill, Peter A Holmans, Markus M Nöthen, Sven Cichon, Marcella Rietschel, Nick Craddock. Mood-Incongruent Psychosis in Bipolar Disorder: Conditional Linkage Analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31. Bipolar Disorders, 2009: 11: 610-620.


Marian L Hamshere, Katherine Gordon-Smith, Liz Forty, Lisa Jones, Sian Caesar, Christine Fraser, Sally Hyde, John Tredget, George Kirov, Ian Jones, Nick Craddock, Daniel J Smith. Age-at-onset in bipolar-I disorder: mixture analysis of 1369 cases identifies three distinct clinical sub-groups. Journal of Affective Disorders. 2009; 116: 23-29.


Smith DJ, Forty L, Russell E, Caesar S, Walters J, Cooper C, Jones I, Jones L, Craddock N. Sub-threshold manic symptoms in recurrent major depressive disorder are a marker for poor outcome. Acta Psychiatrica Scandanavica. 2009; 119: 325-9.


Liz Forty, Lisa Jones, Ian Jones, Daniel J Smith, Sian Caesar, Christine Fraser, Katherine Gordon-Smith, Sally Hyde, Nick Craddock. Polarity at illness onset in bipolar I disorder and clinical course of illness. Bipolar Disorders. 2009; 11: 82-88.


2008

Ferreira MA, O’Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, MacIntyre DJ, MacLean AW, St CD, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Ferrier IN, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N; Wellcome Trust Case Control Consortium. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nature Genetics, 2008: 40: 1056-8.


Moskvina V, Farmer A, Jones IR, Brewster S, Ferrero F, Gill M, Jones LA, Maier W, Mors O, Owen MJ, Perry J, Preisig M, Rietschel M, McGuffin P, Craddock N, Korszun A. Sex Differences in Symptom Patterns of Recurrent Major Depression in Siblings. Depression and Anxiety, 2008: 25; 527-534.


Daniel J Smith, Sarah Kyle, James T Walters, Liz Forty, Carly Cooper, Elen Russell, Sian Caesar, Anne Farmer, Peter McGuffin, Lisa Jones, Ian Jones, Nick Craddock. Differences in depressive symptom profile between males and females. Journal of Affective Disorders. 2008; 108: 279-284.


Liz Forty, Daniel Smith, Lisa Jones, Ian Jones, Sian Caesar, Carly Cooper, Christine Fraser, Katherine Gordon-Smith, Sally Hyde, Anne Farmer, Peter McGuffin, Nick Craddock. Clinical differences between unipolar and bipolar depression. British Journal of Psychiatry. 2008; 192: 388-389.

 


Farmer A, Korszun A, Owen MJ, Craddock N, Jones L, Jones I, Gray J, Williamson RJ, McGuffin P. Medical disorders in subjects with recurrent unipolar depression. British Journal of Psychiatry. 2008; 192: 351-355.


2007

Carly Cooper, Lisa Jones, Emma Dunn, Liz Forty, Sayeed Haque, Femi Oyebode, Nick Craddock, Ian Jones. Clinical Presentation of postnatal and non-postnatal depressive episodes. Psychological Medicine 2007; 37: 1273-80.


Samuel Stoddart, Nick Craddock, Lisa Jones Differentiation of Executive and Attention Impairments in Affective Illness. Psychological Medicine 2007, 37 (11): 1613-1624.


Ian Jones, Marian Hamshere, Jeanne-Marrie Nangle, Philip Bennett, Fiona Middle, Elaine Green, Jess Heron, Ricardo Segurado, David Lambert, Peter Holmans, Aiden Corvin, Mike Owen, Lisa Jones, Michael Gill, Nick Craddock. Bipolar affective puerperal psychosis – genome-wide significant evidence for linkage to chromosome 16. American Journal of Psychiatry 2007, 164: 1099-1104.


Welcome Trust case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447(7145): 661-78.


2006

Liz Forty, Lisa Jones, Stuart Macgregor, Sian Caesar, Caroline Cooper, Andrea Hough, Laura Dean, Subodh Dave, Anne Farmer, Peter McGuffin, Shyama Brewster, Nick Craddock, Ian Jones. Familiality of postpartum depression in unipolar disorder: results of a family study. American Journal of Psychiatry 2006, 163: 1549-1553.


Nigel Williams, Elaine K Green, Stuart Macgregor, Sarah Dwyer, Nadine Norton, Hywel Williams, Rachel Raybould,, Detelina Grozeva, Marian Hamshere, Stanley Zammit, Lisa Jones, Alastair Cardno, George Kirov, Ian Jones, Michael C.O’Donovan, Michael J.Owen, Nick Craddock. Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder. Archives of General Psychiatry 2006, 63; 366-373.


Elaine Green, Rachel Raybould, Stuart Macgregor, Sally Hyde, Allan Young, Michael O’Donovan, Michael Owen, George Kirov, Lisa Jones, Ian Jones, Nick Craddock. Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control sample of over 3000 individuals from the UK. British Journal of Psychiatry 2006, 188; 21-25.


2005

Matthew B. McQueen, B. Devlin, Stephen V. Faraone, Vishwajit L. Nimgaonkar, Pamela Sklar, Jordan W. Smoller, Rami Abou Jamra, Margot Albus, Silviu-Alin Bacanu, Miron Baron, Thomas B. Barrett, Wade Berrettini, Deborah Blacker, William Byerley, Sven Cichon, Willam Coryell, Nick Craddock, Mark J. Daly, J. Raymond DePaulo, Howard J. Edenberg, Tatiana Foroud, Michael Gill, T. Conrad Gilliam, Marian Hamshere, Ian Jones, Lisa Jones, Suh-Hang Juo, John R. Kelsoe, David Lambert, Christoph Lange, Bernard Lerer, Jianjun Liu, Wolfgang Maier, James D. MacKinnon, Melvin G. McInnis, Francis J. McMahon, Dennis L. Murphy, Markus M. No¨then, John I. Nurnberger Jr., Carlos N. Pato, Michele T. Pato, James B. Potash, Peter Propping, Ann E. Pulver, John P. Rice, Marcella Rietschel, William Scheftner, Johannes Schumacher, Ricardo Segurado, Kristel Van Steen, Weiting Xie, Peter P. Zandi, and Nan M. Laird. Combined Analysis from Eleven Linkage Studies of Bipolar Disorder Provides Strong Evidence of Susceptibility Loci on Chromosomes 6q and 8q American Journal of Human Genetics 2005, 77; 582-595.


Elaine Green, Rachel Raybould, Stuart Macgregor, Katherine Gordon-Smith, Jess Heron, Sally Hyde, Detelina Grozeva, Marian Hamshere, Nigel Williams, Michael J Owen, Michael C O’Donovan, Lisa Jones, Ian Jones, George Kirov, Nick Craddock. Operation of the schizophrenia susceptibility gene, Neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Archives of General Psychiatry 2005, 62; 642-648.


Peter McGuffin, Jo Knight, Gerome Breen, Shyama Brewster, Peter R Boyd, Nick Craddock, Mike Gill, Ania Korszun, Wolfgang Maier, Lefkos Middleton, Ole Mors, Michael J Owen, Julia Perry, Martin Preisig, Theodore Reich, John Rice, Marcella Rietschel, Lisa Jones, Pak Sham, Anne E Farmer. Whole genome linkage scan of recurrent depressive disorder from the depression network (DeNt) study. Human Molecular Genetics 2005, 14; 3337-3345.


Lisa Jones, Jan Scott, Sayeed Haque, Katherine Gordon-Smith, Jessica Heron, Sian Caesar, Caroline Cooper, Liz Forty, Sally Hyde, Louisa Lyon, Jayne Greening, Pak Sham, Anne Farmer, Peter McGuffin, Ian Jones, Nick Craddock. Cognitive style in bipolar disorder. British Journal of Psychiatry 2005, 187; 431-437.


Marian Hamshere, Phil Bennett, Nigel Williams, Ricardo Segurado, Alastair Cardno, Nadine Norton, David Lambert, Hywel Williams, George Kirov, Aiden Corvin, Peter Holmans, Lisa Jones, Ian Jones, Michael Gill, Michael O’Donovan, Michael Owen, Nick Craddock. Genome-wide linkage scan in schizoaffective disorder: significant evidence for linkage (LOD=3.54) at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Archives of General Psychiatry 2005, 62; 1081-1088.


David Lambert, Fiona Middle, Marion Hamshere, Ricardo Seguardo, Rachel Raybould, Aiden Corin, Elaine Green, Edmond O’Mahony, Ivan Niclov, Tanya Mulcahy, Sayeed Haque, Sylvia Bort, Phil Bennett, Nadine Norton, Michael Owen, George Kirov, Corinne Lendon, Lisa Jones, Ian Jones, Peter Holmans, Michael Gill, Nick Craddock. Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen provides evidence for suggestive linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22. Molecular Psychiatry 2005, 10; 831-841.


 

Rachel Raybould, Elaine Green, Stuart McGregor, Katherine Gordon-Smith, Jess Heron, Sally Hyde, Sian Caesar, Ivan Nikolov, Nigel Williams, Lisa Jones, Michael O’Donovan, Michael Owen, Ian Jones, George Kirov, Nick Craddock. Bipolar Disorder and polymorphisms in the Dysbindin gene (DTNBP1). Biological Psychiatry 2005, 57:696-701.


2004

Farmer A, Breen G, Brewster S, Craddock N, Gill M, Korszun A, Maier W, Middleton L, Mors O, Owen M, Perry J, Preisig M, Reich T, Reitschel M, Jones L, Jones I, McGuffin P. The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study. BMC Psychiatry, 2004: 4:42.


Sven Cichon, Silvia Buervenich, George Kirov, Nirmala Akula, Albena Dimitrova, Johannes Schumacher, Norman Klopp, Tim Becker, Stephanie Ohlraun, Thomas G. Schulze, Monja Tullius, Magdalena M. Gross, Elaine Green, Lisa Jones, Stefan Krastev, Ivan Nikolov, Marian Hamshere, Ian Jones, Piotr M. Czerski, Anna Leszczynska-Rodziewicz, Pawel Kapelski, Ann Van Den Bogaert, Thomas Illig, Joanna Hauser, Wolfgang Maier, Wade Berrettini, William Byerley, William Coryell, Elliot S. Gershon, John R. Kelsoe, Melvin G. McInnis, Dennis L. Murphy, John I. Nurnberger, Jr, Theodore Reich, William Scheftner, Michael C. O’Donovan, Peter Propping, Michael J. Owen, Marcella Rietschel, Markus M. Nöthen, Francis J. McMahon, & Nick Craddock. Lack of support for a genetic association of the XBP1 promoter polymorphism (-116C®G) with bipolar disorder in probands of European origin. Nature Genetics 2004; 36:783-784.


Craddock N, Jones I, Kirov G, Jones L. The Bipolar Affective Disorder Dimension Scale (BADDS) – a dimensional scale for rating lifetime psychopathology in bipolar spectrum disorders. BMC Psychiatry 2004; 4:19


Korszun A, Moskvina V, Brewster S, Craddock N, Ferrero F, Gill M, Jones IR, Jones LA, Maier W, Mors O, Owen MJ, Preisig M, Reich T, Rietschel M, Farmer AE, McGuffin P. Familiality of Symptom Dimensions in Depression. Archives of General Psychiatry 2004; 61(5):468-474.


2003

Heron J, Jones I, Williams J, Owen, MJ, Craddock N, Jones LA. Self-reported schizotypy and bipolar disorder: demonstration of a lack of specificity of the Kings Schizotypy Questionnaire. Schizophrenia Research 2003; 65:153-158.